Development work on Mobetron system #1 began in November 1993. Intraop Medical (Intraop) demonstrated the major features of the accelerator system in August 1994, and by April 1995, a full working laboratory prototype of the Mobetron was completed.

In September 1996, the Mobetron system was introduced at the Sixth International Intraoperative Radiotherapy Symposium in San Francisco. After extensive acceptance testing, the Mobetron was delivered to the University of California San Francisco (UCSF) and began patient treatments in December 1997. In July 1998, Intraop received approval from the Food and Drug Administration to market the Mobetron in the United States.

During the research and development phase, Intraop conducted the design, assembly and test of its systems, within its facilities as well as the facilities leased by its principal subcontractor, Schonberg Research Corporation. In October 1997, Intraop signed a five-year Contract Manufacturing and Distribution agreement with Siemens Oncology Care Systems, the radiotherapy division of Siemens, A.G.

Intraop featured the Mobetron in September 1998 in Spain at the inaugural meeting of the International Society of IORT (ISIORT). The paper by UCSF on the use of the Mobetron was awarded the Society's "Best Technical Paper," signifying the most important technical contribution to the field of IORT. The Mobetron also received the prestigious "1999 Excellence in Design Award" from  Design Magazine.

Delivery of the first commercial Mobetron system produced by Siemens was to University Hospitals of Cleveland, where patient treatments began in July 1999. Additional Mobetron units have been delivered to University of Louisville Health Center Hospital (Louisville, Kentucky), University of North Carolina at Chapel Hill, Methodist Hospital of Indianapolis, Mayo Clinic in Scottsdale, Arizona and Tokyo University in Japan.

In April 2001, Intraop assumed responsibility for worldwide distribution of the Mobetron. The CE Mark, required for European medical sales, was received in October 2001. A new manufacturer, CDS Systems , was appointed in October 2002. Mobetron systems from Intraop's new contract manufacturer will begin shipping in 2003 to hospitals in Europe, Asia and the United States.

Please refer to our Treatment Centers page for a listing of hospitals that have Mobetron treatment systems.